Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen. This results in mast cell degranulation and release of histamine and other inflammatory mediators.
This is also called an anaphylactic reaction (anaphylaxis – harmful) or allergic reaction. It has two presentations: Immediate reaction: This reaction starts within 5-30 minutes and subsides in 60 minutes. Late phase reaction: This starts in 2-8 hours and lasts 2-3 days.
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